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(1998) Impaired motor coordina-tion in mice lacking prion protein. Yet, with an investigative strategy so radically differentfrom more “traditional” approaches, many researchers remain suspicious of qualita-tive studies. Inflammatory blood laboratory levels as markers ofprosthetic joint infection: a systematic review and meta-analysis. Heart rate variability in patients with mild to moderate heartfailure: effects of neurohormonal modulation by digoxin and ibopamine. Wu J, Davis MD, Owens RA (2001) A Rep recognition sequence is necessary but not suf? -cient for nicking of DNA by adeno-associated virus type-2 Rep proteins. The bill was signed into law at the Truman Library,with former President Harry S. As mentioned earlier in The importance ofautoimmunity during the anti-tumor T cell response and its relationship to Treg dysfunctionand the predisposition of autoimmune and cancer patients to contract other autoimmunediseases section, there are two types of memory T cells that are crucial for not onlypreventing a recurrence of the tumor, but also inadvertently causing cancer-inducedautoimmunity. However in spiteof early S phase entry, the lung cells from p53-null MDM2 transgenic mice showfewer DNA replication origin ?ring events compared to lung cells from p53-nullmice at the onset of S phase [ 25]. Brian Berman from the University of Maryland completed a six-month trial of acupuncture in 570 patients with osteoarthritis of theknee.4 All participants were age fifty or older and had significant painin their knee the month before joining the study, but had never expe-rienced acupuncture. Understandingsymptom complexes, meridians, and the insertion of the needles requiressome degree of training

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Thislanguage-based research has identified at leastthree distinguishable qualities of dyspnea—(a)air hunger, (b) work/effort, and (c) chest tight-ness—and has shown that these qualities mayarise from different physiological sources (Binkset al., 2002; Lansing et al., 2000; Moosavi etal., 2000; Schwartzstein & Christiano, 1996).Air hunger arises from an increased ventilatorydrive from chemoreceptor stimuli and is strong-est when ventilation is insufficient (Banzett etal., 1989; Banzett et al., 1990; Manning et al.,1992; Wright & Branscomb, 1954).

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